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Friday 23 January 2015

Thursday 22 January 2015

CSIR-JRF/DBT-JRF/GATE-LIFE SCIENCES ASPIRANTS

Under alkaline conditions, DNA is more stable than RNA because
(A) RNA forms secondary structures
(B) RNA is a single stranded molecule
(C)RNA has uracil in place of thymidine
(D)RNA is susceptible to hydrolysis

CSIR-JRF/DBT-JRF/GATE-LIFE SCIENCES ASPIRANTS

Which one of the following modifications is common to both protein and DNA?
(A) SUMOylation (B) Nitrosylation
(C)Methylation (D) Ubiquitination

‎CSIR-JRF/DBT-JRF/GATE-LIFE SCIENCES ASPIRANTS

Transport activities in cell membranes are carried by ____________; whereas fluidity of membranes is maintained by ____________.
(A) lipids; proteins
(B) proteins; nucleic acids
(C) lipids; nucleic acids
(D) proteins; lipids

‎CSIR-JRF/DBT-JRF/GATE-LIFE SCIENCES ASPIRANTS

A nick in a DNA moIecule can be detected by which of the following methods?
(A) Nested PCR
(B) Primer extcnsion
(C) RT-PCR
(Dl Karyotyping

‎CSIR-JRF/DBT-JRF/GATE-LIFE SCIENCES ASPIRANTS

Ribonuclease has four disulfide bonds which were reduced by Dithiothreitol in presence of SM urea. These reagents were removed by diaIysis so that the protein could refoId and the disulfide bonds reformed. If the reformation of S-S bonds occurred randomly, he expected recovery of [he biological activtiy would be
(A) 100%
(B) 80%
(C> 0.95 %
(D) 95 %

‎CSIR-JRF/DBT-JRF/GATE-LIFE SCIENCES ASPIRANTS

A cybrid is a hybrid carrying
a. cytoplasms of two different plants
b. genomes of two different plants
c. genome of one plant and cytoplasms of both plants
d. genomes and cytoplasms of two different plants

‎CSIR-JRF/DBT-JRF/GATE-LIFE SCIENCES ASPIRANTS

In gram staining of gram negative bacteria, the crystal violet-iodine complex formed will be washed away after addition of
(A) safranin solution (B) ethyl acetate.
(C) water. (D) alcohol

‎CSIR-JRF/DBT-JRF/GATE-LIFE SCIENCES ASPIRANTS

Hybridomas are formed by fusing antibody-producing splenocytes with
a. viruses b. bacteria
c. myeloma cells d. red blood cells

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Which one of the following is an ABC transporter?
(A)multidrug resistance protein (B) acetylcholine receptor
(C)bacteriorhodopsin (D) ATP synthase

‎CSIR-JRF/DBT-JRF/GATE-LIFE SCIENCES ASPIRANTS

An AT-rich DNA fragment with a melting temperature (T.) of 60 °C will contain approximately
(a) 16 GC pairs and 6 AT pairs
(b) 6 GC pairs and 21 AT pairs
(c) 8 GC pairs and 19 AT pairs
(d) 15 GC pairs and 15 AT pairs

‎CSIR-JRF/DBT-JRF/GATE-LIFE SCIENCES ASPIRANTS

A mixture of Arginine, Phenylalanine and Histidine was fractionated using cation exchange chromatography at neutral pH. The amino acids were eluted with an increasing salt gradient. Identify the correct order of elution.
(A) Arginine, Histidine, Phenylalanine
(B) Phenylalanine, Histidine, Arginine
(C) Histidine, Phenylalanine, Arginine
(D) Arginine, Phenylalanine, Histidine

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The product(s) resulting from the hydrolysis of maltose is/are
(A) a mixture of α-D-Glucose and β-D-Glucose
(B) a mixture of D-Glucose and L-Glucose
(C) α-D-Glucose only
(D) β-D-Glucose only

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____ is frequently found on the surface of B cells co-expressed with ____. These two classes are co-expressed not by class switching but by alternative processing of a primary RNA transcript. Both molecules expressed on the single mature B cell have the same binding specificity for antigen.
a) IgA & IgG
b) IgD & IgM
c) IgE & IgA
d) IgG & IgM
e) IgM & IgE

‎CSIR-JRF/DBT-JRF/GATE-LIFE SCIENCES ASPIRANTS

Which one of the following is TRUE regarding organization of human chromosomes? It is made up of
(A) histones that are acidic proteins.
(B) extra-chromosomal circular DNA.
(C) chromatin that consists of DNA and basic proteins.
(D) non-chromosomal DNA.

‎CSIR-JRF/DBT-JRF/GATE-LIFE SCIENCES ASPIRANTS

In a batch culture of Penicillium chrysogenum, the maximum penicillin synthesis occurs during the
(A) lag phase
(B) exponential phase
(C) stationary phase
(D) death phase

‎CSIR-JRF/DBT-JRF/GATE-LIFE SCIENCES ASPIRANTS

n Sanger's method of DNA sequencing, the growing DNA chain are terminated because....
A..DNA polymerase is not very processive
B..a radioactive nucleotide is incorporated
C..the substrate become limiting
D..a phosphodiester bond cannot be made

Wednesday 21 January 2015

‎CSIR-JRF/DBT-JRF/GATE-LIFE SCIENCES ASPIRANTS



The oligosaccharide part of glycoproteins is either N-linked or O-linked. The amino acid residues through which these oligosaccharides are attached to polypeptide are
(A) Asn and Thr
(B) Asp and Ser
(C) Ser and Lys
(D) Gln and Ser
MHC

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Based on the dissociation constant Kd, the protein - ligand pair that has the strongest interaction is
(A) insulin and insulin receptor (Kd = 1 × 10^10).
(B) avidin and biotin (Kd = 1 × 10^15).
(C) HIV surface protein and anti-HIV IgG (Kd = 4 × 10^10).
(D) calmodulin and calcium (Kd = 3 × 10^6).

‎CSIR-JRF/DBT-JRF/GATE-LIFE SCIENCES ASPIRANTS

In nature, the horizontal gene transfer across bacteria is mediated by
(A) gene cloning followed by transformation 
(B)conjugation and transformation
(C) conjugation only 
(D) transformation only

‎CSIR-JRF/DBT-JRF/GATE-LIFE SCIENCES ASPIRANTS

n plant tissue culture, differentiation of callus to root requires
(A) high auxin and low cytokinin. (B) low auxin and high cytokinin.
(C) low auxin and low cytokinin. (D) high auxin and high cytokinin.

‎CSIR-JRF/DBT-JRF/GATE-LIFE SCIENCES ASPIRANTS

Which one of the following statements is true with regard to the nature of viroids and prions?
(A) Viroids are DNA and prions are RNA
(B) Viroids are protein and prions are RNA
(C) Viroids are RNA and prions are protein
(D) Both are made of protein

‎CSIR-JRF/DBT-JRF/GATE-LIFE SCIENCES ASPIRANTS

In higher plants, the light harvesting molecules are
(A) vitamin D and cytochrome C.
(B) cytochrome C and cholorophyll.
(C) anthocyanin and carotenoid.
(D) chlorophyll and carotenoid.

‎CSIR-JRF/DBT-JRF/GATE-LIFE SCIENCES ASPIRANTS

IgE is secreted by : 
a) Mast cell
b) Basophils
c) Eosinophils
d) Plasma cells
e) Neutrophil

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Addition of casein to solid media and picking up bacterial colonies that form clear zone is termed as
(A) differential enrichment. (B) streaking.
(C) serial dilution. (D) selective enrichment.

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The A260/A280 ratio of a DNA sample was observed to be 1.2. An increase in this ratio can be obtained by subjecting the DNA sample to
(A) phenol extraction
(B) trichloroacetic acid treatment
(C) butanol extraction
(D) all of the above can be used

‎CSIR-JRF/DBT-JRF/GATE-LIFE SCIENCES ASPIRANTS

The oxidation of glycolate to glyoxylate during photorespiration occurs in
(A) bundle sheath cells. (B) mesophyll cells.
(C) mesenchymal cells. (D) parenchymal cells.

CSIR-JRF/DBT-JRF/GATE-LIFE SCIENCES ASPIRANTS

The binding of oxygen to hemoglobin is affected by
(A) hemoglobin concentration. (B) partial pressure of oxygen.
(C) bicarbonate concentration. (D) 2,3-biphosphoglyceric acid

‎CSIR-JRF/DBT-JRF/GATE-LIFE SCIENCES ASPIRANTS

The melting point of unsaturated fatty acid
(A) is not related to the number of double bonds.
(B) increases with increase in the number of double bonds.
(C) is higher than that of its corresponding saturated fatty acid.
(D) decreases with increase in the number of double bonds.

CSIR-JRF/DBT-JRF/GATE-LIFE SCIENCES ASPIRANTS

Diploid cells have
a. two chromosomes
b. two sets of chromosomes
c. one set of chromosomes
d. two pairs of homologous chromosomes

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The synthesis of proteins requires 20 standard amino acids in the living systems. However, some organisms use selenocysteine as an additional amino acid for synthesizing proteins. Selenocysteine is biosynthesized from
(A) Cysteine
(B) Serine
(C) Threonine
(D) Proline

‎CSIR-JRF/DBT-JRF/GATE-LIFE SCIENCES ASPIRANTS

Which one of the following microscopic techniques is best suited to visualize the topology and distribution of transmembrane protein of a cell membrane?
(A) Scanning electron microscopy
(B) Transmission electron microscopy
(C) Freeze-fracture electron microscopy
(D) Thin-section electron microscopy

‎CSIR-JRF/DBT-JRF/GATE-LIFE SCIENCES ASPIRANTS

A bacterial culture contained 32x10^6 cells after 2.5 hours of exponential growth. If the doubling time was 30 min, what was the initial population number in this culture?
(A) 20x10^4 cells
(B) 10x10^5 cells
(C) 40x10^5 cells
(D) 16x10^6 cells

‎CSIR-JRF/DBT-JRF/GATE-LIFE SCIENCES ASPIRANTS

Receptors for steroid hormones are found 
a) on plasma membrane 
b) cytoplasm 
c) in mitochondria 
d) on ribosomes

‎CSIR-JRF/DBT-JRF/GATE-LIFE SCIENCES ASPIRANTS

The process of purification and recovery of a product in biotechnology is known as
(A) upstream processing. (B) downstream processing.
(C) incubation. (D) formulation.

‎CSIR-JRF/DBT-JRF/GATE-LIFE SCIENCES ASPIRANTS

he process of purification and recovery of a product in biotechnology is known as
(A) upstream processing. (B) downstream processing.
(C) incubation. (D) formulation.

CSIR-JRF/DBT-JRF/GATE-LIFE SCIENCES ASPIRANTS

Cori cycle integrates body metabolism to
(A) resynthesize glucose from lactate in the liver
(B) oxidize acetyl CoA in the muscle
(C) generate urea in the kidney
(D) generate glucose from acetyl CoA in the liver

CSIR-JRF/DBT-JRF/GATE-LIFE SCIENCES ASPIRANTS

Regenerative medicine aims at
(A) discovering small molecules. (B) generating therapeutic proteins.
(C) growing tissues and organs. (D) identifying genetic mutations.

Tuesday 20 January 2015

‎CSIR-JRF/DBT-JRF/GATE-LIFE SCIENCES ASPIRANTS

Which of the following features would you NOT expect to find in heterogeneous nuclear RNA (hnRNA)?
A. intron
B. polycistronic coding
C. polyadenylation at 3'-end
D. 5-' cap structure
E. U nucleotides

CSIR-JRF/DBT-JRF/GATE-LIFE SCIENCES ASPIRANTS

Which of the following features would you NOT expect to find in heterogeneous nuclear RNA (hnRNA)?
A. intron
B. polycistronic coding
C. polyadenylation at 3'-end
D. 5-' cap structure
E. U nucleotides

CSIR-JRF/DBT-JRF/GATE-LIFE SCIENCES ASPIRANTS

The "Southern" technique involves:
A. the detection of RNA fragments on membranes by specific radioactive antibodies.
B. the detection of DNA fragments on membranes by a radioactive DNA probe.
C. the detection of proteins on membranes using a radioactive DNA probe.
D. the detection of proteins on membranes using specific radioactive antibodies.

‎GovernmentJobGroup(State and Central Govt.Jobs Info)

Ques - किस तत्व के साथ पानी आने पर आग लग जाती है ?
A. जिंक
B. सोडियम
C. मैग्नीशियम
D. फासफोरस

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भारत के किस प्रधानमन्त्री का जन्म दिन 4 साल मेँ एक बार मनाया जाता है?
a) अटल बिहारी वाजपेय
b) लाल बहादुर शास्त्री
c) मोराजी देसाई

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4. संक्षिप्त शब्द RDX से तात्पर्य है–
(A) Radiation Detection Through X-ray
(B) Research Development Explosive
(C) Rotatory Device Explosive
(D) उपर्युक्त में से कोई नहीं

GovernmentJobGroup(State and Central Govt.Jobs Info)

Question: हाथियों का देश किसे कहा जाता है ?
(1) अफ्रीका
(2) थाइलैंड
(3) लाओस
(4) फिनलैंड

GovernmentJobGroup(State and Central Govt.Jobs Info)

प्रश्न= 2015 वर्ल्ड कप क्रिकेट मैच में ब्रांड
अम्बेसडर किसे चुना गया है।।।।
(1) सचिन तेंदुलकर
(2) गावस्कर
(3) राहुल द्रविड़
(4) कोई नही
SAIL recruitment 2015
Total Vacancy - 901 Posts
Qualification - 10,12,Diploma,ITI,Grad,Eng
More Details & apply click here -> http://bit.ly/1BsS8LT

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Veer Dwivedi's photo.

Thursday 15 January 2015